Could the placebo effect be bullshit? (with Literal Banana)

What this episode covers

Read the full transcript here. • Is the placebo effect bullshit? Are "open-label" placebos just as effective as "closed-label" placebos? How do placebos differ from dummies? Is the placebo effect just a kind of scientific-sounding "woo"? How does social priming differ from word priming? Why is it important in research to have both placebo and no-treatment groups? What is the Hawthorne effect? What is the John Henry effect? When is it useful to express effect sizes using Cohen's d ? If there's not a placebo effect, then what's really going on in cases where it seems like there is one? Is meditation a kind of placebo treatment for mental states? How can researchers believe that people's mental states are important and yet that the placebo effect doesn't exist? What is stress-induced analgesia? Does the nocebo effect (if it exists) provide reason to think that the placebo effect exists? Where do psychosomatic effects fit into this picture? What have animal studies found about the placebo effect? • Literal Banana is literally a banana who became interested in human social science through trying to live among them. After escaping from a high-tech produce delivery start-up, she now lives among humans and attempts to understand them through their own sciences of themselves. Follow Literal Banana on Twitter at @literalbanana (https://twitter.com/literalbanana). • Further reading • "A Case Against the Placebo Effect", by Literal Banana (https://carcinisation.com/2024/11/13/a-case-against-the-placebo-effect/) • "Placebo interventions for all clinical conditions", by Asbjørn Hróbjartsson and Peter Gøtzsche (https://pubmed.ncbi.nlm.nih.gov/20091554/) • "Tears", by Kevin Simler (https://meltingasphalt.com/tears/) • Staff • Spencer Greenberg (https://www.spencergreenberg.com/) — Host / Director • Josh Castle (mailto:[email protected]) — Producer • Ryan Kessler (https://tone.support/) — Audio Engineer • Uri Bram (https://uribram.com/) — Factotum • WeAmplify (https://www.weamplify.info/) — Transcriptionists • Music • Broke for Free (https://freemusicarchive.org/music/Broke_For_Free/Something_EP/Broke_For_Free_-_Something_EP_-_05_Something_Elated) • Josh Woodward (https://www.joshwoodward.com/song/AlreadyThere) • Lee Rosevere (https://archive.org/details/MusicForPodcasts04/Lee+Rosevere+-+Music+for+Podcasts+4+-+11+Keeping+Stuff+Together.flac) • Quiet Music for Tiny Robots (https://www.freemusicarchive.org/music/Quiet_Music_for_Tiny_Robots/The_February_Album/05_Tiny_Robot_Armies) • wowamusic (https://gamesounds.xyz/?dir=wowamusic) • zapsplat.com (https://www.zapsplat.com/music/summer-haze-slow-chill-out-house-track-with-a-modern-pop-feel-warm-piano-chords-underpin-the-track-with-warm-pads-and-a-repetitive-synth-arpeggio/) • Affiliates • Clearer Thinking (https://www.clearerthinking.org/) • GuidedTrack (https://guidedtrack.com/) • Mind Ease (https://mindease.io/) • Positly (https://positly.com/) • UpLift (https://www.uplift.app/)

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