COX-2 Inhibitors to Increase Effectiveness of Emergency Contraception

Emergency contraception use has an effectiveness of about 70%. Join host, Geoff Wall, as he reviews new literature to see if COX-2 inhibition improves that rate. The GameChangerEmergency contraception (EC) is safe and effective but overall efficacy rates could be better. COX-2 inhibitors may enhance the effectiveness of EC but require multiday dosing. HostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint Health ReferenceLi RHW, Lo SST, Gemzell-Danielsson K, et al. Oral emergency contraception with levonorgestrel plus piroxicam: a randomised double-blind placebo-controlled trial. Lancet. 2023 Sep 9;402(10405):851-858. doi: 10.1016/S0140-6736(23)01240-0. Epub 2023 Aug 16. Erratum in: Lancet. 2023 Sep 9;402(10405):850. PMID: 37597523.https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(23)01240-0.pdf Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Describe the selection of the particular COX-2 medication used in this study 2. Discuss the implications of the COX-2 augmentation with patients0.05 CEU/0.5 HrUAN: 0107-0000-23-322-H01-PInitial release date: 10/9/2023Expiration date: 10/9/2024Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram