CPAP and cardiovascular risk: what’s the relationship?

In this episode of OnAir, we ask whether treatment-adherent OSA patients could be lowering their cardiovascular risk while they sleep. Professor Frédéric Gagnadoux and host Nina Wiklund explore the design, results and implications of his recent 5,000-patient cohort study, which indicates that CPAP can deliver a significant reduction in major adverse cardiovascular events. They ask which patients are likely to benefit, discuss the importance of hours of usage, and consider the tools that clinicians can use to support therapy adherence. Listen to learn about the potential impact of CPAP therapy on the cardiovascular health of your OSA patients. Guest: Prof. Frédéric Gagnadoux - Head of the department of respiratory and sleep medicine, University Hospital of Angers, France. Host: Nina Wiklund is ResMed’s Global Medical Marketing Content Lead, and has a burning enthusiasm for clinical research. She is especially interested in the additional insights and possibilities real-world evidence can add to existing RCTs.  References and useful links: Gerves-Pinquie C, Bailly S, Goupil F, Pigeanne T, Launois S, Leclair-Visonneau L, et al.; Pays de la Loire Sleep Cohort Study Group. (2022). Positive airway pressure adherence, mortality and cardiovascular events in sleep apnea patients. Am J Respir Crit Care Med, 206, pp. 1393–1404. DOI: 1164/rccm.202202-0366OC Sánchez-de-la-Torre M, Gracia-Lavedan E, Benitez ID, et al. Adherence to CPAP Treatment and the Risk of Recurrent Cardiovascular Events: A Meta-Analysis. 2023;330(13):1255–1265. doi:10.1001/jama.2023.17465 ERS 2023 Workshop: CPAP therapy and cardiovascular outcomes – what have we learned from real-life cohorts? The podcast OnAir, with Clinical Respiratory News (CRN) is a medical education non-promotional for healthcare professionals organised by ResMed. Learn more at https://webinars.resmed.eu/podcasts-list/. This podcast is intended for healthcare professionals only. Disclaimer: This programme is non promotional and is sponsored by ResMed. The speakers are being compensated and/or receiving an honorarium from ResMed in connection with this programme. The content contained in this programme was jointly developed by the speakers and ResMed, and is not eligible for continuing medical education (CME) credits. Listen to OnAir with Clinical Respiratory News, the podcast that brings you fresh insights and thought-provoking discussions about hot topics in sleep and breathing health. © ResMed