CRACKCast E126 - Diabetes Mellitus and Disorders of Glucose Homeostasis

Core questions:   Define DKA. List 6 potential triggers of DKA. Describe the pathophysiology of DKA. (Fig 118.1) How is DKA managed in children? In adults? What are the epidemiologic risk factors for cerebral edema in DKA? What are signs and symptoms of cerebral edema? How do you manage a pt with DKA and suspected cerebral edema? List 5 complications of DKA management List five common serious infections in diabetics and how they are managed. How does hypoglycemia classically present? List 10 causes of hypoglycemia Describe the treatment of hypoglycemia What is the definition of hyperglycemic, hyperosmolar state? Contrast DKA and HHS (Table 118.2) What is the pathophysiology of HHS? How is HHS managed?   WiseCracks:   Why are urine ketones less sensitive for DKA than serum ketones? When do you give NaHCO3 to a patient with DKA? What is euglycemic DKA? What is the differential diagnosis of hypoglycemia in a patient who does not have DM? What would you add to the differential diagnosis in a pt who has DM?