CRACKCast E162 – Opioids

Core questions: List 6 commonly abused opioids (Table 156:1) Describe the opioid toxidrome (list opioid effects on Neuro, Resp, Ophtho, CV, GI, Derm) List opioid preparations associated with the following presentations: Long QTc → Prolonged QRS → Seizures → Hallucinations →) Sensorineural hearing loss → Serotonin syndrome →   i) What is the dose of narcan? ii) What is the duration of action? iii) How do you administer a narcan infusion? What opioid overdoses/ingestions need longer than 6 hours of observation? What is the clinical presentation of opioid withdrawal? What are risk factors for opioid withdrawal? List 3 medications effective for opioid withdrawal. What is the number one killer of people under 50? What is Suboxone? How do you do a Suboxone induction? WiseCracks: List 5 ddx for opioid intoxication (CNS + resp depression, + miosis). What opioids don't cause miosis? Risk factors for opioid overdose? What is NAPE? Narcan induced pulmonary edema. Difference between a "body packer" and "body stuffer"?