Cranberry- A-type vs. B-type proanthocyanidins: the same molecule class, different linkage, completely different function

from NutraSift: The nutraceutical innovation podcast · host Siftlink SA

Cranberry has A-type PACs (anti-adhesion); grape seed has B-type PACs (antioxidant/vascular). The only structural difference is one additional ether bond between flavanol units. That single bond changes the entire biological function. Most consumers and many companies don't know there are two types, let alone that they do completely different things.Publications of interest:https://pmc.ncbi.nlm.nih.gov/articles/PMC10215713/, https://pmc.ncbi.nlm.nih.gov/articles/PMC3823508/, https://pmc.ncbi.nlm.nih.gov/articles/PMC8389005/

Episode metadata supplied by the publisher feed · Published Jun 18, 2026

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