Cranberry: The botanical whose mechanism is anti-adhesion, not anti-microbial

Cranberry A-type PACs don't kill bacteria. They prevent uropathogenic E. coli from attaching to bladder walls by inhibiting P-fimbriae adhesion. This is a fundamentally different mechanism from antibiotics , it doesn't create resistance, it prevents colonization. The mechanism is so specific that there's a validated dose-response: 36mg PAC-A/day is the threshold. Below that, nothing happens. Above it, significant UTI reduction. This is pharma-level mechanism specificity in a berry.Publications of interest:https://pubmed.ncbi.nlm.nih.gov/16055161/https://pmc.ncbi.nlm.nih.gov/articles/PMC2873556/https://pubmed.ncbi.nlm.nih.gov/10872208/