Crossing Borders: Exploring the Blood-Brain Barrier

Dr Fiona McLean, ARUK Research Fellow, University of Dundee is joined by fellow experts Dr Kate Harris and Dr Sophie Morse, to explore the intricacies of the blood-brain barrier and its pivotal role in dementia research.They discuss pioneering methods in overcoming the barrier for drug delivery, the significance of endothelial cells in barrier integrity, and novel approaches in treating neurodegenerative diseases. The conversation also touches on the collaborative nature of neuroscience, offering invaluable insights for newcomers to the field. Don’t miss this deep dive into the forefront of dementia research.Meet the guests:Dr Sophie Morse is a Research Fellow & UK DRI Emerging Leader at Imperial College London, within the UK Dementia Research Institute. Sophie is a biomedical engineer who leads a research group exploring the use of Therapeutic Ultrasound for Brain Diseases.Dr Kate Harris is an Academic Track Alzheimer’s Research UK Fellow in Drug Discovery at Newcastle University. Kate is working on finding new drug targets for neurodegenerative disease in neuroinflammation.Links mentioned in the show:Rapid short-pulses of focused ultrasound and microbubbles deliver a range of agent sizes to the brain – https://bit.ly/41PFvuh--A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.Leave us a tip:https://dementia-researcher.captivate.fm/supportFollow us on social media:https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/https://www.twitter.com/demrescommunityhttps://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.socialDownload and Register with our Community App:https://www.onelink.to/dementiaresearcherWe gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.Subscribe to our sister show 'Dementia Researcher The Blogs':https://podfollow.com/dementia-researcher-blogs