EPISODE · Jun 9, 2026 · 3 MIN
Crotonylation, Hold the Line
from Base by Base - Music · host Gustavo Barcelos Barra
This release contains only the music track from Base by Base Episode 389. Song title: Crotonylation, Hold the LineOriginal Base by Base episode: 389: Crotonylation impedes c-Myc oncogenic activity Article metadata:Article title: Crotonylation impedes c-Myc oncogenic activityJournal: PNASDOI: 10.1073/pnas.2530020123Reference: https://doi.org/10.1073/pnas.2530020123 Lyrics:Verse 1Under white lights, the signals start to spark,A switch on a protein in the dark.A tiny mark where the messages align,And suddenly the noise learns how to decline. Pre-ChorusHands on the bench, eyes on the screen,A lock clicks shut where it shouldn’t have been.If the grip is broken, the storm can slow,One quiet change in the afterglow. ChorusCrotonylation, hold the line,Keep that wildfire from crossing the signs.K289, K298—stay in place,Let the runaway lose the race.Crotonylation, hold the line. Verse 2When the mark is missing, the binder comes close,Skp2 pulls tight like a knot in a rope.The pages turn faster, the volume climbs,More genes lit up in relentless time. BridgeAnd there’s a variant turning the key—K298N,Less of the mark, and the pull begins.In living tissue the shadow can grow,But the map says where the pressure flows.Break the handshake, change the deal,Turn down the drive, make the damage kneel. Final ChorusCrotonylation, hold the line,Keep that wildfire from crossing the signs.K289, K298—stay in place,Let the runaway lose the race.Cut the Skp2 chain in time,Crotonylation—hold the line.
What this episode covers
This release contains only the music track from Base by Base Episode 389. Song title: Crotonylation, Hold the LineOriginal Base by Base episode: 389: Crotonylation impedes c-Myc oncogenic activity Article metadata:Article title: Crotonylation impedes c-Myc oncogenic activityJournal: PNASDOI: 10.1073/pnas.2530020123Reference: https://doi.org/10.1073/pnas.2530020123 Lyrics:Verse 1Under white lights, the signals start to spark,A switch on a protein in the dark.A tiny mark where the messages align,And suddenly the noise learns how to decline. Pre-ChorusHands on the bench, eyes on the screen,A lock clicks shut where it shouldn’t have been.If the grip is broken, the storm can slow,One quiet change in the afterglow. ChorusCrotonylation, hold the line,Keep that wildfire from crossing the signs.K289, K298—stay in place,Let the runaway lose the race.Crotonylation, hold the line. Verse 2When the mark is missing, the binder comes close,Skp2 pulls tight like a knot in a rope.The pages turn faster, the volume climbs,More genes lit up in relentless time. BridgeAnd there’s a variant turning the key—K298N,Less of the mark, and the pull begins.In living tissue the shadow can grow,But the map says where the pressure flows.Break the handshake, change the deal,Turn down the drive, make the damage kneel. Final ChorusCrotonylation, hold the line,Keep that wildfire from crossing the signs.K289, K298—stay in place,Let the runaway lose the race.Cut the Skp2 chain in time,Crotonylation—hold the line.
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Crotonylation, Hold the Line
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