Cut the Static, Save the Signal episode artwork

EPISODE · May 16, 2026 · 3 MIN

Cut the Static, Save the Signal

from Base by Base - Music · host Gustavo Barcelos Barra

This release contains only the music track from Base by Base Episode 368. Song title: Cut the Static, Save the SignalOriginal Base by Base episode: 368: PARP1 and Amyloid: Protecting Neurons in a Familial AD Model Article metadata:Article title: PARP1 deficiency mitigates amyloid pathology, neurodegeneration, and cognitive decline in a familial Alzheimer’s disease modelJournal: PNASDOI: 10.1073/pnas.2525028123Reference: Jhaldiyal A., Kumari M., Guttman L. C., et al. PARP1 deficiency mitigates amyloid pathology, neurodegeneration, and cognitive decline in a familial Alzheimer’s disease model. PNAS (2026). DOI: 10.1073/pnas.2525028123 Lyrics:Verse 1Bright screen glow in the after-hoursLittle shards in the synapse airA whispered storm that never showersLeaves a fracture everywhere Pre-ChorusWhen the damage starts to flickerYou can hear the cells go thinBut there’s a switch inside the circuitLet the quiet fight begin ChorusCut the static, save the signalDon’t let the memory burnTurn down PAR, break the spiralLet the tide reverse and turnLess made, more cleared—hold the lineWe can slow the fall with time Verse 2Oligomers knock like broken rhythmSet off alarms in neural codeBut if PARP1 can’t feed the systemThe heavy chain won’t overload BridgeLower the blade that makes the fragmentsShift the gears that shape the cutRaise the cleaner in the currentSo the dark can’t pile up Final ChorusCut the static, save the signalDon’t let the memory burnTurn down PAR, break the spiralLet the tide reverse and turnLess made, more cleared—hold the lineWe can draw new maps from time

Episode metadata supplied by the publisher feed · Published May 16, 2026

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This release contains only the music track from Base by Base Episode 368. Song title: Cut the Static, Save the SignalOriginal Base by Base episode: 368: PARP1 and Amyloid: Protecting Neurons in a Familial AD Model Article metadata:Article title: PARP1 deficiency mitigates amyloid pathology, neurodegeneration, and cognitive decline in a familial Alzheimer’s disease modelJournal: PNASDOI: 10.1073/pnas.2525028123Reference: Jhaldiyal A., Kumari M., Guttman L. C., et al. PARP1 deficiency mitigates amyloid pathology, neurodegeneration, and cognitive decline in a familial Alzheimer’s disease model. PNAS (2026). DOI: 10.1073/pnas.2525028123 Lyrics:Verse 1Bright screen glow in the after-hoursLittle shards in the synapse airA whispered storm that never showersLeaves a fracture everywhere Pre-ChorusWhen the damage starts to flickerYou can hear the cells go thinBut there’s a switch inside the circuitLet the quiet fight begin ChorusCut the static, save the signalDon’t let the memory burnTurn down PAR, break the spiralLet the tide reverse and turnLess made, more cleared—hold the lineWe can slow the fall with time Verse 2Oligomers knock like broken rhythmSet off alarms in neural codeBut if PARP1 can’t feed the systemThe heavy chain won’t overload BridgeLower the blade that makes the fragmentsShift the gears that shape the cutRaise the cleaner in the currentSo the dark can’t pile up Final ChorusCut the static, save the signalDon’t let the memory burnTurn down PAR, break the spiralLet the tide reverse and turnLess made, more cleared—hold the lineWe can draw new maps from time

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