Cystic Fibrosis Diabetes

This episode delivers a definitive analysis of cystic fibrosis-related diabetes, the most common extra-pulmonary complication of cystic fibrosis. We explore its unique mixed pathophysiology, combining primary insulin insufficiency from progressive pancreatic fibrosis with fluctuating insulin resistance driven by chronic pulmonary inflammation. Listeners will learn to identify the clinical impact on nutritional status and lung function, understand why oral glucose tolerance tests are required for screening, and see why insulin remains the primary therapeutic intervention.