De-extinction: Genetics, conservation, and lessons from 'dire wolves' episode artwork

EPISODE · Sep 17, 2025 · 28 MIN

De-extinction: Genetics, conservation, and lessons from 'dire wolves'

from Tiny Matters

Back in April, a company called Colossal Biosciences announced that they had brought dire wolves — ancient canines of Game of Thrones fame — back from extinction. The internet went wild. But while some media outlets proclaimed the return of a long-gone species, many scientists shot back on social media that these weren’t really dire wolves, they were just genetically engineered grey wolves. Suddenly everybody had an opinion on what de-extinction is, what it is not, and whether or not we should be doing things like this in the first place. In this episode, we talk to scientists who have been working in this area for a while, and they not only share their thoughts on these wolves — they completely change our understanding of the term “de-extinction.”Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter!Links to the Tiny Show and Tell stories are here and here. All Tiny Matters transcripts and references are available here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Back in April, a company announced that they had brought dire wolves — ancient canines of Game of Thrones fame — back from extinction. But did they?

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De-extinction: Genetics, conservation, and lessons from 'dire wolves'

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This episode was published on September 17, 2025.

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Back in April, a company called Colossal Biosciences announced that they had brought dire wolves — ancient canines of Game of Thrones fame — back from extinction. The internet went wild. But while some media outlets proclaimed the return of a...

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