Derek Thompson on AI, abundance, and human progress episode artwork

EPISODE · Apr 23, 2025 · 53 MIN

Derek Thompson on AI, abundance, and human progress

from Possible · host Reid Hoffman

Why can the United States government help make a vaccine in a year but not build a high-speed train in a reasonable timeframe? What if our biggest problems—affordable housing shortages, energy limits, and scientific slowdowns—aren’t inevitable, but chosen? This week, Reid and Aria sit down with Derek Thompson—staff writer at The Atlantic and host of the podcast Plain English—to explore how a scarcity mindset is holding American society back. They cover how AI can revolutionize scientific discovery; what Operation Warp Speed got right; and why real progress depends on bold policy, not just better technology. Plus, Reid joins Derek in the hotseat for some “Too Much, Too Little, or Just Right?”—a game co-created with ChatGPT to discuss ideas in Derek’s new best-selling book, Abundance.  For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/  Select mentions:  Abundance by Ezra Klein and Derek Thompson “The Anti-Social Century”  Every Cure co-founder Dr. David Fajgenbaum  Topics: 1:06 – Episode introduction 2:34 – What year would Derek choose to be born and why? 7:14 – What can AI do as a co-author that Ezra Klein can't, and what are Ezra's irreplaceable strengths? 9:08 – AI's impact on the future of work — what AI can and can't do — and what the enduring role of humans will be. 12:00 – The situation with current tariffs, and the potential fixes or silver linings. 14:28 – Operation Warp Speed and other examples of abundance in the U.S. and beyond. 19:39 – What specific government policies could effectively leverage AI to speed up the creation of abundance? 22:40 – Midroll 22:49 – Derek and Reid play a fun game based on Abundance: “Too much, too little, or just right?”  30:46 – What's needed to better incentivize scientific progress and foster innovation? 39:22 – How could society and our relationship with technology be reframed to combat the loneliness epidemic? 45:08 – Derek identifies specific policies that currently hinder abundance and suggests new ones that could promote it. 49:45 – Rapid-fire Questions Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.

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Derek Thompson on AI, abundance, and human progress

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