Derm: Lentigo Maligna: Free MSRA Podcast

🧑‍⚕️ FREE MSRA PODCAST – Lentigo Maligna: Melanoma In Situ Unpacked🎯 Everything you need to revise lentigo maligna for the MSRA. From clinical clues to management and prevention—get all the essentials, fast.Key Learning Points🔍 Definition• Lentigo maligna is a melanoma in situ—malignant melanocytes limited to the epidermis.• Grows slowly on sun-damaged skin, usually the face or neck of older adults.💡 Causes & Risk Factors• Cumulative UV exposure (decades in the sun)• Fair skin, age >60, history of skin cancer, immunosuppression• Think “chronic sun damage” not acute sunburn🧬 Pathophysiology• UV light causes DNA mutations in melanocytes• Slow, radial (horizontal) spread within the epidermis• Can progress to invasive melanoma by breaching the basement membrane🩺 Clinical Features• Flat, slow-growing, irregularly pigmented patch (brown/black)• Asymmetrical, ill-defined borders, colour variegation• Usually on face/neck, >6mm diameter• Usually asymptomatic• Doesn’t darken after recent sun, unlike freckles💡 Mnemonic: ABCDE for Pigmented LesionsA – AsymmetryB – Border irregularityC – Colour variationD – Diameter >6mmE – Evolution (change over time)Lentigo maligna often ticks several of these!📝 Differential Diagnosis (Mnemonic: F-S-A-L-M)F: FreckleS: Seborrhoeic keratosisA: Actinic keratosisL: Lentigo malignaM: Melanoma (other types)Also: solar lentigo, superficial spreading melanoma, ephelides🔬 Investigations• Clinical exam (ABCDE checklist)• Dermoscopy• Definitive diagnosis = Skin biopsy (punch or excision)💊 Management• Surgical excision with clear margins is gold standard• Mohs micrographic surgery for facial lesions (tissue-sparing, high cure)• If unfit for surgery: Imiquimod cream, radiotherapy, cryotherapy (less reliable)• Any suspicious lesion → Refer to dermatology📈 Prognosis• Excellent if caught in situ and treated• ~5% progress to invasive melanoma (much higher risk if untreated)• Post-treatment: regular skin surveillance⚠️ Complications• Progression to invasive melanoma (major risk)• Recurrence if incomplete removal• Cosmetic concerns, side effects of treatment• Increased risk of further skin cancers📎 More MSRA Revision for Lentigo Maligna:📝 Revision Notes: https://www.passthemsra.com/topic/lentigo-maligna-revision-notes/💬 Flashcards: https://www.passthemsra.com/topic/lentigo-maligna-flashcards/🧠 Accordion Q&A: https://www.passthemsra.com/topic/lentigo-maligna-accordion-qa-notes/🚀 Rapid Quiz: https://www.passthemsra.com/topic/lentigo-maligna-rapid-quiz/🧪 Full Quiz: https://www.passthemsra.com/quizzes/lentigo-maligna/🎓 Dermatology Course: https://www.passthemsra.com/courses/dermatology-for-the-msra/🌐 For more free & premium revision resources:https://www.passthemsra.com#MSRA #LentigoMaligna #MelanomaInSitu #DermatologyMSRA #MSRARevision #PassTheMSRA #FreeMSRA #ABCDE #SkinCancer #MSRAFlashcards