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DermSurgery Digest At The Microscope: PRAME

First published

02/21/2024

Genres:

health

medicine

Summary

This inaugural episode of a new DermSurgery Digest bonus content aptly named “At the Microscope” will share the latest research and techniques in dermatopathology as it is applicable to dermatologic surgery. In this episode, contributors will review recent literature around preferably expressed antigen in melanoma (PRAME) as a useful marker to support a suspected diagnosis of melanoma. Contributors to this podcast include Naomi Lawrence, MD, Dermatologic Surgery Digital Content Editor; Ashley...

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DermSurgery Digest

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    Description: In this episode of the DermSurgery Digest, you’ll hear a roundtable discussion on the articles featured in the May 2024 issue of Dermatologic Surgery, published by the American Society for Dermatologic Surgery. Contributors to this podcast include Dermatologic Surgery Digital Editor Naomi Lawrence, MD; DermSurgery Digest Co-host Michael Renzi, MD; Tara Jennings, MD; and Megan McClean, MD; with special guest reviewers Anne Chapas, MD; and Divya Srivastava, MD. In this podcast, surgical oncology and reconstruction articles are presented first and general dermatologic surgery and cosmetics articles follow, beginning at 1:11:53.Your feedback is encouraged. Please contact [email protected].

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    DermSurgery Digest At The Microscope: PRAME

    Release Date: 02/21/2024

    Description: This inaugural episode of a new DermSurgery Digest bonus content aptly named “At the Microscope” will share the latest research and techniques in dermatopathology as it is applicable to dermatologic surgery. In this episode, contributors will review recent literature around preferably expressed antigen in melanoma (PRAME) as a useful marker to support a suspected diagnosis of melanoma. Contributors to this podcast include Naomi Lawrence, MD, Dermatologic Surgery Digital Content Editor; Ashley Elsensohn, MD, MPH, DermSurgery Digest at the Microscope co-host; Ami Greene, MD; Tara Jennings, MD; Yesul Kim, MD; and Catherine Motosko, MD. Articles featured include: Lezcano C, Jungbluth AA, Nehal KS, et al. PRAME expression in melanocytic tumors. Am J Surg Pathol. 2018;42:1456–1465. Lezcano C, Jungbluth AA, Busam KJ. Comparison of immunohistochemistry for PRAME with cytogenetic test results in the evaluation of challenging melanocytic. Am J Surg Pathol. 2020;44:893–900. de Wet J, Plessis PJD, Schneider JW. Staged Excision of Lentigo Maligna of the Head and Neck: Assessing Surgical Excision Margins With Melan A, SOX10, and PRAME Immunohistochemistry. Am J Dermatopathol. 2023 Feb 1;45(2):107-112. doi: 10.1097/DAD.0000000000002354. Turner N, Ko CJ, McNiff JM, Galan A. Pitfalls of PRAME Immunohistochemistry in a Large Series of Melanocytic and Nonmelanocytic Lesions With Literature Review. Am J Dermatopathol. 2024 Jan 1;46(1):21-30. doi: 10.1097/DAD.0000000000002584.Please submit questions to be answered in future episodes to [email protected].

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