DESTINY-Breast11 and Surrogate Endpoints episode artwork

EPISODE · Jul 1, 2026 · 6 MIN

DESTINY-Breast11 and Surrogate Endpoints

from PharmOncology · host Ming-Hei Tai

Thoughts on using pCR as a surrogate endpointDESTINY-Breast11: https://pubmed.ncbi.nlm.nih.gov/41130363/Clinical Cancer Research publication on pCR, EFS and OS: https://aacrjournals.org/clincancerres/article/26/12/2838/82378/Pathologic-Complete-Response-after-NeoadjuvantBMJ publication on pCR, EFS and OS: https://www.bmj.com/content/375/bmj-2021-066381FDA-sponsored analysis: https://pubmed.ncbi.nlm.nih.gov/24529560/KATHERINE trial: https://www.nejm.org/doi/full/10.1056/NEJMoa1814017

Episode metadata supplied by the publisher feed · Published Jul 1, 2026

Thoughts on using pCR as a surrogate endpointDESTINY-Breast11: https://pubmed.ncbi.nlm.nih.gov/41130363/Clinical Cancer Research publication on pCR, EFS and OS: https://aacrjournals.org/clincancerres/article/26/12/2838/82378/Pathologic-Complete-Response-after-NeoadjuvantBMJ publication on pCR, EFS and OS: https://www.bmj.com/content/375/bmj-2021-066381FDA-sponsored analysis: https://pubmed.ncbi.nlm.nih.gov/24529560/KATHERINE trial: https://www.nejm.org/doi/full/10.1056/NEJMoa1814017

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Thoughts on using pCR as a surrogate endpointDESTINY-Breast11: https://pubmed.ncbi.nlm.nih.gov/41130363/Clinical Cancer Research publication on pCR, EFS and OS:...

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