Diabetes, Metformin, and Age Related Macular Degeneration

In this episode, Dr. Gloria Wu discusses a study from the February 2026 issue of the Journal of Ophthalmology Retina that explores the relationship between long-term Metformin use and age-related macular degeneration (AMD) in diabetic patients. The research found that patients who took Metformin for five or more consecutive years had a significantly lower risk of developing both dry and wet AMD compared to those who did not take the medication. While the protective effect was strongest after six years of use, even shorter durations showed some benefit, suggesting that Metformin may offer a proactive way for diabetics to safeguard their vision as they age.