颠覆认知的研究:口腔微生物与消化道疾病的密切关系 episode artwork

EPISODE · May 28, 2026 · 13 MIN

颠覆认知的研究:口腔微生物与消化道疾病的密切关系

from 消化肝病前沿资讯

本期播客揭示口腔微生物与消化系统健康的深度关联,颠覆传统认知。口腔作为第二大微生物栖息地,其菌群失衡可通过血液、肠道途径“远行”至消化道,参与胃食管反流病、食管癌、胃癌、结直肠癌等多种疾病进程,特定细菌如牙龈卟啉单胞菌、具核梭杆菌更与癌症发生发展及预后密切相关。节目还探讨防治思路,强调口腔健康是守护全身健康的关键一环。00:06口腔菌群与消化健康初探00:56菌群失衡的两种转移途径01:47具核梭杆菌的精准定植02:27口腔菌入肠的条件与风险03:20GERD与口腔菌群的关联04:03GERD菌群变化的炎症影响04:57巴雷特食管的菌群信号05:44食管癌的菌群类型差异06:47牙龈卟啉单胞菌的致癌机制07:54口腔菌削弱抗癌免疫能力08:36胃癌中非Hp的口腔菌作用09:26口腔菌激活胃炎相关通路10:26口腔菌在胃癌全程的角色11:11结直肠癌与具核梭杆菌11:59具核梭杆菌的致癌机理12:55防治策略与预防重要性

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颠覆认知的研究:口腔微生物与消化道疾病的密切关系

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