Dr. Chris Rhodes on Fasting Without Hunger

EPISODE · Apr 2, 2026 · 45 MIN

Dr. Chris Rhodes on Fasting Without Hunger

from AGEIST · host David Stewart

Dr. Chris Rhodes explains what fasting is actually doing in the body, where the benefits begin, and why shorter fasting windows may not deliver what many people expect. He walks us through the science behind fasting mimetics, including how his team studied a 36-hour fast and built a supplement around the molecules that arise during it. You come away with a clearer way to think about hunger control, food noise, metabolic health, and the tradeoffs between fasting, appetite-suppressing drugs, and everyday eating. He also offers a sharp take on saturated fat hype and makes the case for a more personal, evidence-based future in nutrition.Save 20% on Mimio with code: AGEIST20Big Announcement: The Super Age Games are here! Join us November 7th in NYC for an entirely new longevity competition.Special Thanks to Our SponsorsLMNT Electrolytes: Our #1 electrolytes for optimal hydration, and their new 12oz sparkling cans are officially for sale online! Get a free Sample Pack of LMNT’s most popular drink mix flavors with any purchase by using our link here. Find your favorite LMNT flavor, or share with a friend.Fatty15: C15:0 is the first essential fatty acid to be discovered in over 90 years, and Fatty15 is on a mission to optimize your C15:0 levels to help support your long-term health and wellness—especially as you age. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/AGEIST and using the code “AGEIST” at checkout.Our Place: The top cookware brand for beautiful, non-toxic, PFA-free pots and pans. Use the code “AGEIST” for 10% off at fromourplace.com. Key Moments"What most people do not realize is that they are often not getting the benefits of fasting that they think that they are getting."“From a biological perspective, it takes around 24 hours without food in order to actually activate that metabolic switch where you're going from, you know, fed metabolism, glucose metabolism, over into ketone metabolism and fasting metabolism.”"Let's find patterns that work specifically for you."Connect with Chris RhodesWebsite: mimiohealth.comLinkedIn: linkedin.com/in/chrishrhodesConnect with AGEISTNewsletterInstagramWebsiteLinkedInClick Here for the full interview transcript.Say hi to the AGEIST team!

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Dr. Chris Rhodes on Fasting Without Hunger

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