EPISODE · Nov 16, 2025 · 13 MIN
Dr Dean Ornish Study: Multi-modal lifestyle intervention Alzheimer’s disease
from The Longevity Podcast: Optimizing HealthSpan & MindSpan · host Dung Trinh
Send us Fan MailWe examine a phase two randomized controlled trial testing a 20-week, intensive lifestyle program for people with MCI or early Alzheimer’s and find evidence of measurable improvement. We unpack the four-pillar design, the cognitive and biological results, and the adherence threshold that drove success.• Participant profile and trial structure for MCI and early AD• Four pillars explained: diet, exercise, stress care, social support• Clinical outcomes improving daily function and global status• Biomarkers shifting: Aβ42/40 ratio, microbiome, telomeres• Dose response and why 71% adherence mattered• Strengths, limits, and feasibility in real-world care• Practical steps to build structure and track adherenceThis podcast is created by Ai for educational and entertainment purposes only and does not constitute professional medical or health advice. Please talk to your healthcare team for medical advice. Never miss an episode—subscribe on your favorite podcast app!
What this episode covers
Send us Fan Mail We examine a phase two randomized controlled trial testing a 20-week, intensive lifestyle program for people with MCI or early Alzheimer’s and find evidence of measurable improvement. We unpack the four-pillar design, the cognitive and biological results, and the adherence threshold that drove success. • Participant profile and trial structure for MCI and early AD • Four pillars explained: diet, exercise, stress care, social support • Clinical outcomes improving daily functi...
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Dr Dean Ornish Study: Multi-modal lifestyle intervention Alzheimer’s disease
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