Dr. Geoff Dow – New Clinical Trial for Chronic Babesiosis: Tafenoquine, Malaria Drugs, and Hope for Lyme-Linked Fatigue episode artwork

EPISODE · Feb 25, 2026 · 38 MIN

Dr. Geoff Dow – New Clinical Trial for Chronic Babesiosis: Tafenoquine, Malaria Drugs, and Hope for Lyme-Linked Fatigue

from Integrative Lyme Solutions with Dr. Karlfeldt · host Dr. Michael Karlfeldt

Is chronic babesiosis finally getting the scientific attention it deserves?In this episode of Integrative Lyme Solutions, Dr. K sits down with Dr. Geoff Dow, CEO & President of Sixty Degrees Pharmaceuticals, to discuss a groundbreaking clinical trial targeting chronic babesiosis — a common and often overlooked Lyme co-infection. Originally developed for malaria prevention, the drug Tafenoquine (brand name Kodatef®) is now being studied for its potential to treat persistent Babesia infections and Lyme-related fatigue.They explore the science behind red blood cell parasites, how Babesia differs from malaria, why chronic babesiosis remains controversial, and what makes this new trial the first FDA-reviewed IND study focused on chronic disease. If you or a loved one struggle with Lyme-related fatigue, relapsing babesiosis, or limited treatment options, this conversation offers cautious optimism and a closer look at the future of targeted therapies.Key Takeaways:0:00 Introduction3:10 From Malaria Drug Development to Lyme Co-Infections6:45 How Babesia Infects Red Blood Cells and Causes Fatigue10:40 Why Chronic Babesiosis Is Still Controversial14:50 No FDA-Approved Drugs Specifically for Babesiosis18:30 New Clinical Trials for Chronic and Relapsing Babesiosis24:00 Measuring Fatigue as a Primary Endpoint in Chronic DiseaseResources Mentioned:Sixty Degrees Pharmaceuticals - https://www.sixtydegreespharma.comKodatef® (Tafenoquine) Information - Available via company website aboveMount Sinai (Clinical Trial Site) - https://www.mountsinai.orgYale Babesiosis Case Series (Referenced Study) - https://medicine.yale.eduMedical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. ____________________________________WORK WITH DR. KARLFELDT:The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies available. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor, contact us at:📞 208-338-8902📧 [email protected]🌐 TheKarlfeldtCenter.com____________________________________📖 FREE EBOOK: Breaking Free From Lyme: A Comprehensive Guide to Healing and RecoveryGet your copy at: store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse code LYMEPODCAST for 100% off____________________________________CONNECT WITH DR. KARLFELDT:Instagram: instagram.com/thekarlfeldtcenterFacebook: facebook.com/thekarlfeldtcenter____________________________________MORE PODCASTS FROM DR. KARLFELDT:🎙 The Dr. K Show — Integrative medicine, functional medicine,  biohacking, and longevity for optimizing health and performance.🎙 Integrative Cancer Solutions — Evidence-based integrative therapies and real patient stories for those navigating a cancer diagnosis.Explore all shows on https://www.youtube.com/@KarlfeldtCenter____________________________________

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Dr. Geoff Dow – New Clinical Trial for Chronic Babesiosis: Tafenoquine, Malaria Drugs, and Hope for Lyme-Linked Fatigue

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