Dr. Len Schleifer, CEO of Regeneron: Betting on Science and Saving a President

On this episode of inSpired, Mike Rockefeller, Co-Chief Investment Officer of Woodline, sits down with Dr. Leonard Schleifer, Co-Founder, President & CEO of Regeneron, at its headquarters in New York. Len reflects on the 38-year journey of building Regeneron alongside co-founder Dr. George Yancopoulos, the company's deep pipeline, and the extraordinary story of treating President Trump for COVID-19. They explore the growth runway for Eyela and Dupixent, its late-stage pipeline spanning obesity, multiple myeloma, anticoagulation, and the C5 franchise, as well as the Regeneron Genetics Center, curing genetic deafness, AI in drug discovery, and the company's disciplined M&A philosophy. A candid take on science-first drug development and what it takes to succeed in the biotechnology industry going forward. This is inSpired.Recorded May 6, 2026._____________________________________________________________________________________________________________________________00:00  inSpired with Dr. Leonard Schleifer01:49  Founding Regeneron in 198808:04  Working with Dr. George Yancopoulos11:44  Top Moments and the EYLEA Approval15:05  Treating President Trump for COVID19:22  EYLEA and EYLEA HD Today20:18  Dupixent and the Type 2 Franchise23:20  Next Generation Immunology29:39  Obesity: A GLP That Lowers Cholesterol33:42  Lynozyfic in Multiple Myeloma34:50  Factor XI Anticoagulation39:46  The C5 Franchise42:48  The Regeneron Genetics Center48:06  Curing Genetic Deafness50:03  AI in Drug Discovery52:17  M&A Philosophy55:47  Succession and Advice for the Next Len_____________________________________________________________________________________________________________________________Mike Rockefeller is the Co-CIO of Woodline® Partners LP ("Woodline"), manager of the Woodline | Spire funds. All opinions expressed by Mike and podcast guests are solely their own opinions and do not reflect the opinion of Woodline.Guests appearing on this podcast may maintain, or may have maintained, business relationships with Woodline or its affiliates. The views expressed by any guest do not constitute an endorsement or testimonial of Woodline.This podcast is for educational and informational purposes only, is not directed at any investors or potential investors in any Woodline fund and should not be relied upon as a basis for investment decisions. Funds managed by Woodline, including the Woodline Spire℠ funds, may maintain positions in the securities discussed in this podcast. Any discussion of the past performance of any investment, sector, or market is not indicative of any future results.www.woodlinepartners.comBe sure to follow us on X/Twitter: @inSpiredPodXEpisode Credits:Directed by & Artwork Designed by: Brian Thompson / BT Design & CreativeProduced, Edited, and Mixed by: Dillon Mortensen FilmsMusic Licensed through: Epidemic Sound