Dr. Paul Kolodzik on GLP-1s and Modern Metabolism

Dr. Paul Kolodzik spent 25 years in emergency medicine watching the long-term consequences of preventable disease. Now, he’s helping patients reverse metabolic syndrome using continuous glucose monitors (CGMs), low-carb nutrition, and strength training. In this episode, Dr. Kolodzik explains why blood sugar spikes—not cholesterol—may be the most urgent threat to long-term health. You’ll also hear why he believes wearables and strategic use of GLP-1 medications can radically change your health trajectory.How long will you live? Take our quiz today to find out! Visit ageist.com/longevityquizThanks to Our SponsorsTroscriptions — Precision, pharmaceutical-grade nootropics for peak performance. Whether you need laser focus, mental clarity, or a boost in cognitive endurance, Troscriptions delivers science-backed results. Use code: AGEIST for 10% off, or click here.LMNT Electrolytes — Our number one electrolytes for optimal hydration. Listeners receive a free 8-serving sample pack with their purchase at DrinkLMNT.com/AGEIST. Our Place – Our top cookware brand for non-toxic, PFA-free pots and pans. Use code “AGEIST” for 10% off at fromourplace.com Chapters(00:15) Introduction to Metabolic Health and CGMs(03:28) Understanding Fatty Liver Disease and Carbohydrate Impact(06:10) The Role of Continuous Glucose Monitors (CGMs)(09:06) Insulin Resistance and Metabolic Syndrome(12:04) The Relationship Between Blood Sugar and Weight Gain(15:18) Dietary Approaches to Managing Blood Sugar(18:08) The Importance of Personalization in Diet(21:11) Inflammation, Brain Health, and Blood Sugar(24:14) Understanding A1C and Blood Sugar Metrics(29:13) Understanding Blood Sugar Levels(35:15) The Role of Exercise in Insulin Resistance(41:08) Integrating GLP-1 Medications with CGMs(47:25) The Importance of Continuous Glucose Monitoring(51:07) Empowerment Through Data and Personal Health ManagementKey MomentsFatty liver disease isn’t from eating too much fat — it’s, for most people, excessive carb intake.Once I see it, I can’t unsee it. And then you know what’s going on with your blood sugar physiology.Strength training reverses insulin resistance. Your muscles are soaking up more insulin and more blood glucoseConnect with Dr. Paul KolodzikCGM Doctor — https://cgm-doctor.comMetabolicMDs Practice — https://metabolicmds.comBook:The Continuous Glucose Monitor Revolution for Non-Diabetics — https://www.amazon.com/dp/B0BHL5YZXVSocial Media: LinkedIn — linkedin.com/in/paulkolodzik/Check out the full interview transcriptConnect With AGEISTNewsletterInstagramWebsiteSay hi to the AGEIST team!