Dr. Scott McMahon | Chronic Lyme, mold illness and the CIRS connection doctors miss episode artwork

EPISODE · Jul 27, 2026 · 42 MIN

Dr. Scott McMahon | Chronic Lyme, mold illness and the CIRS connection doctors miss

from Integrative Lyme Solutions with Dr. Karlfeldt · host Dr. Michael Karlfeldt

What if the reason your Lyme treatment isn't working has nothing to do with the infection itself?In this episode of Integrative Lyme Solutions, Dr. K talks with pediatrician Dr. Scott McMahon, Medical Director at Moldco, about the immune system reaction that keeps so many chronic Lyme patients sick long after the bacteria are gone. Dr. McMahon explains how dead pathogen fragments can keep triggering the innate immune system, why standard labs like CBC and CRP almost always miss it, and which specific markers (TGF-beta 1, MMP9, C4a) tell the real story. He also walks through his treatment approach with binders, a low-amylose diet, and VIP peptide therapy, and shares data from his work on children with recurrent headaches, stomach issues, and PANS/PANDAS whose symptoms resolved once the underlying inflammatory response was addressed.This conversation covers what chronic inflammatory response syndrome (CIRS) is, why it so often overlaps with Lyme and mold illness, and how the hypothalamus, blood-brain barrier, and autonomic nervous system get pulled into the mix. If you've been treating the infection but still aren't getting better, this episode explains the piece that's likely missing.Key Takeaways:0:00 Introduction0:53 Immune response drives chronic Lyme symptoms2:53 Key labs standard testing misses6:30 Dead pathogen fragments trigger the immune system9:33 Binders, diet and VIP reset the response16:57 Kids' unexplained symptoms trace back to CIRS30:00 CIRS disrupts the blood-brain barrier and hormones35:26 Low-cost telehealth model closes the access gap Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902Resources:Moldco - https://www.moldco.comSurviving Mold (Dr. Ritchie Shoemaker) - https://www.survivingmold.comIncellDx (Dr. Bruce Patterson) - https://www.incelldx.comKlinghardt Institute (Dr. Dietrich Klinghardt) - https://klinghardtinstitute.com/Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions.

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