Dr. Sigrun Hallmeyer & Dr. William Gradishar - SERENA-6 & Early Endocrine Resistance

What if we could detect endocrine resistance before it shows up on scans?In this CHM Conversations episode, Dr. Sigrun Hallmeyer and Dr. William Gradishar break down the SERENA-6 trial and what it means for the future of HR-positive, HER2-negative metastatic breast cancer.From early detection of ESR1 mutations using ctDNA to switching therapy before clinical progression, this discussion explores how molecular monitoring is reshaping treatment decisions, extending progression-free survival, and preserving quality of life.The conversation also dives into real-world implementation, patient experience, cost considerations, and what comes next as oncology moves toward more personalized, biology-driven care.A must-watch for clinicians navigating the evolving endocrine landscape.🎧 Watch more expert-led oncology conversations from CHM Conversations.#BreastCancer #HRPositive #Oncology #ESR1 #ctDNA #SERENA6 #EndocrineTherapy #MedicalOncology #PrecisionOncology #CommunityHealthMedia–Thanks for watching!Our podcasts are also available on: • Spotify - https://spotf.fi/chm-podcast • Amazon Music - https://amazn.so/chm-podcast • Apple Podcast - https://podcasts.apple.com/us/podcast/community-health-media/id1837428248 • Castbox - https://castbox.fm/vh/6735434 • Goodpods - https://goodpods.com/profile/chm-111066 • iHeartRadio - https://iheart.com/podcast/291542082 • Pocket Casts - https://pca.st/3ncdh11o–Community Health Media (CHM) is your full service healthcare communications partner, combining our production expertise with targeted multi-channel campaigns. We connect companies and healthcare brands with key opinion leaders, patients, and consumers through compelling content and live experiences.We’re an integrated marketing company that produces world-class content and curated peer to peer live experiences.We specialize in: • Peer to peer interviews, panels & round-tables • Curated live events & conferences • Professional in-depth content & research updates • Interactive learning modules & webinars • Live & on-demand webcasts & podcastsLearn more about us here - https://communityhealth.media