Drug–Drug Interaction Primer: A Compendium of Case Vignettes for the Practicing Clinician

Serves as a practical guide for clinicians, focusing on drug-drug interactions (DDIs), particularly those involving psychotropic agents. The content uses numerous case vignettes to illustrate complex pharmacokinetic interactions, mainly centered on the cytochrome P450 (P450) enzyme system, which is crucial for drug metabolism. It explains core concepts like substrate, inhibitor, and inducer relationships, detailing how co-administering certain drugs can dangerously alter blood levels of others, potentially leading to toxicity or loss of therapeutic efficacy. The book also includes tables and appendices summarizing drugs metabolized by various P450 and UGT (glucuronosyltransferase) enzymes.You can listen and download our episodes for free on more than 10 different platforms:https://linktr.ee/pharmacy_simpleProduced by:https://www.podcaistudio.com/