Drugs n Stuff 320 Why Steroid Cycles Stop Working (And How to Keep Growing) + PED QA episode artwork

EPISODE · Jul 20, 2026 · 1H 6M

Drugs n Stuff 320 Why Steroid Cycles Stop Working (And How to Keep Growing) + PED QA

from Think BIG Bodybuilding · host Think BIG Bodybuilding Media

Why do steroids stop producing the same gains over time? In this episode of Drugs N Stuff, Scott McNally and Dave Crosland explain why simply running more drugs for longer eventually leads to diminishing returns—and how experienced bodybuilders structure long growth phases to keep making progress. Plus, we answer your questions on testosterone isocaproate, DHB, Dutasteride, Retatrutide, NAD+, P-21, sauna use, TRT injection frequency and much more. ⏱ TIMESTAMPS 0:00 Why Steroids Eventually Stop Working 1:00 Support Our Sponsors 3:45 How to Plan a 12-Month Growth Phase 13:40 Start Low, Build Slowly & Extend Your Cycle 20:30 Testosterone Isocaproate Half-Life Explained 24:10 Can You Re-Sensitize Yourself to Stimulants? 29:40 Scott's Experience with P-21 31:40 Selank: Scott's Honest Experience 32:50 Low-Dose Testosterone + DHB for a Specific Look 37:00 Sauna Benefits While Using PEDs 41:00 Can Retatrutide Reduce Addiction? 45:00 NAD+ Benefits & Can You Overdo Mitochondria? 48:45 Why Some Lifters Are Leaving Daily TRT Injections 49:45 Does Dutasteride Protect Against Dianabol Hair Loss? 51:50 Why Hydrochlorothiazide Is NOT Potassium Sparing 54:30 LSD as a Treatment for Depression 56:00 Uncle Dave's Wisdom 1:04:00 We Need to Buy Dave a Horn Check out all our affiliates at http://www.thinkbigbodybuilding.com UK Blood Work Get your Labs done by Dave in the UK : https://evalbloodanalysis.com/home/ Support the Podcast Patreon — Help keep the show growing. Even $5/month makes a difference. https://www.patreon.com/thinkbigbodybuilding Sponsors TRUE NUTRITION — Custom supplements for serious lifters Use code THINK to save https://www.truenutrition.com/THINK STROM SPORTS — Performance supplements trusted by athletes UK: https://tinyurl.com/ydmbfa54 US: https://stromsportsus.com Supplement Source Canada — Top brand supplements with fast shipping http://www.supplementsource.ca Merch Official THINK BIG Merch — Train, represent, support the brand https://think-big.printify.me/products

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Drugs n Stuff 320 Why Steroid Cycles Stop Working (And How to Keep Growing) + PED QA

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