《都市異聞錄》 - 粒線體功能障礙與神經退化性疾病新突破專題 episode artwork

EPISODE · Aug 14, 2025 · 2 MIN

《都市異聞錄》 - 粒線體功能障礙與神經退化性疾病新突破專題

from 都市異聞錄 · host 島編

由Giovanni Marsicano、Luigi Bellocchio和Étienne Hébert Chatelain領導的研究團隊,創造了一個人工受體,能夠直接在粒線體內激活G蛋白,以提升細胞能量輸出。當在阿茲海默症和額顳葉失智症的小鼠模型上進行測試時,該工具使粒線體活性和記憶表現都恢復正常。 「這項研究首次建立了粒線體功能障礙與神經退化性疾病相關症狀之間的因果關係,表明粒線體活性受損可能是神經元退化發生的根源,」Marsicano說。 這些發現挑戰了粒線體損傷僅僅是神經退化後果的主流觀點。相反地,它們表明衰竭的細胞發電廠積極推動認知能力下降。 免費追蹤,更新資訊不漏接: https://open.firstory.me/join/cmdvv73j803w701w6gkn29qcs 加入會員,支持節目: https://open.firstory.me/user/cmdvv73j803w701w6gkn29qcs 留言告訴我你對這一集的想法: https://open.firstory.me/user/cmdvv73j803w701w6gkn29qcs/comments Powered by Firstory Hosting

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《都市異聞錄》 - 粒線體功能障礙與神經退化性疾病新突破專題

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