E84 Masterclass with Carl Brown on Rectal Cancer

Dr. Carl Brown (https://twitter.com/drcarl_vancouvr?s=20) is a colorectal surgeon at St. Paul’s Hospital in Vancouver, British Columbia. He gave us a masterclass on rectal cancer, starting really with the history of rectal cancer surgery to the evidence around neodjuvant therapy and then giving us a peek at the future of rectal cancer treatment. We then discuss how we should best adopt new technology such a TEM or taTME. A reminder to listeners that we know have the transcripts for all our episodes available on the CJS website – this is a handy written resource to go over, especially for detailed masterclasses like this one. As always, we welcome your feedback on twitter @canjsurg or via email at [email protected]. Brown on Twitter: @drcarl_vancouvrLinks:1. Techniques and technology evolution of rectal cancer surgery: a history of more than a hundred years. https://www.tandfonline.com/doi/full/10.1080/13645706.2016.11983812. Swedish Rectal Cancer trial in NEJM on preop radiotherapy- https://www.nejm.org/doi/full/10.1056/nejm199704033361402.3. German Rectal cancer trail on preop vs post op radiotherapy - https://www.nejm.org/doi/full/10.1056/nejmoa0406944. Dutch rectal cancer trail on preoperative radiotherapy plus TME (published in NEJM) - https://www.nejm.org/doi/full/10.1056/nejmoa0105805. The "Holy" Plane of Rectal Cancer surgery by Healds - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291757/6. Rates of Circumferential Resection Margin Involvement Vary Between Surgeons and Predict Outcomes in Rectal Cancer Surgery (Phil Quirke) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1422458/7. CCTG CO.28 primary endpoint analysis: Neoadjuvant chemotherapy, excision and observation for early rectal cancer, the NEO trial. https://ascopubs.org/doi/abs/10.1200/JCO.2021.39.15_suppl.35088. Transanal endoscopic microsurgery: a review (by Dr. Brown in CJS) - http://canjsurg.ca/vol57-issue2/57-2-127/9. Hey, I just did a new operation!: Introducing innovative procedures and devices within an academic health center. https://pubmed.ncbi.nlm.nih.gov/24866545/10. IDEAL Collaboration: https://www.ideal-collaboration.net/