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Early career investigator highlight: Dr. Raissa Nobrega episode artwork

EPISODE · Aug 31, 2018 · 10 MIN

Early career investigator highlight: Dr. Raissa Nobrega

from Springer Nature · host Springer Nature

Patients with sickle cell disease often experience severe pain as a result of vaso-occlusive episodes. Typically their pain is managed with opioids, however some patients experience continued and increasing pain, believed to be as a result of opioid-induced hyperalgesia or tolerance. Many patients go on to develop chronic pain which is thought to have a neuropathic component, for which opioids are ineffective. Ketamine has been suggested as an adjuvant to opioids to treat chronic and acute pain. In this episode, we meet an Early Career Investigator, Dr. Raissa Nobrega, who has a passion for paediatric pain management and who recently published an exploratory study into the patient characteristics that affect the response to ketamine and opioids in these patients. Article link: https://www.nature.com/articles/pr2017283

What this episode covers

Patients with sickle cell disease often experience severe pain as a result of vaso-occlusive episodes. Typically their pain is managed with opioids, however some patients experience continued and increasing pain, believed to be as a result of opioid-induced hyperalgesia or tolerance. Many patients go on to develop chronic pain which is thought to have a neuropathic component, for which opioids are ineffective. Ketamine has been suggested as an adjuvant to opioids to treat chronic and acute pain. In this episode, we meet an Early Career Investigator, Dr. Raissa Nobrega, who has a passion for paediatric pain management and who recently published an exploratory study into the patient characteristics that affect the response to ketamine and opioids in these patients. Article link: https://www.nature.com/articles/pr2017283

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Early career investigator highlight: Dr. Raissa Nobrega

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How long is this episode of Springer Nature?

This episode is 10 minutes long.

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This episode was published on August 31, 2018.

What is this episode about?

Patients with sickle cell disease often experience severe pain as a result of vaso-occlusive episodes. Typically their pain is managed with opioids, however some patients experience continued and increasing pain, believed to be as a result of...

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