Engineering Nanomedical Systems

This tutorial will cover general problems and approaches to the design of engineered nanomedical systems. An example to be covered is the engineering design of programmable multilayered nanoparticles (PMNP) to control a multi-sequence process of targeting to rare cells in-vivo, re-targeting to intracellular sites, and controlling of final gene/drug delivery. Therapeutic genes can be manufactured inside living cells as a "nanofactory" under the control of these molecular biosensors providing feedback- controlled single cell medicine.