Engineering Recombinantly Expressed Antiviral Lectins

Cyanovirin-N, or CV-N for short, is a broadly binding molecule to glycopeptides and glycan structures on viral envelope spikes, which allows for screening of these structures by protein-interaction based sensor technologies.Dr. Irene Maier, Lecturer at the Medical University of Vienna, Austria, examines the molecular understanding of immune diseases. Maier has designed new antiviral CV-N variants and measured their binding constants to glycoproteins exposed at the surface of immune-stimulating cells, which has the potential to revolutionize treatments against viral infections.Find out more about Irene's work on ResearchGateRead the original research: https://www.jove.com/de/t/63541/engineering-antiviral-agents-via-surface-plasmon-resonance