EPISODE · Jun 8, 2026 · 50 MIN
Ensuring Success: Managing Expectations and Treatment Adherence
from Defocus Media Eyecare and Optometry Podcast Network · host Drs. Glover & Lyerly
Dry eye disease (DED) impacts countless individuals, and while therapies like Xiidra® (lifitegrast ophthalmic solution) 5% have proven effective,1 ensuring consistent patient compliance remains a challenge for eye care professionals. Xiidra, which can improve signs and symptoms as early as two weeks,1* is most effective when used consistently. Based on insights shared in the Defocus […]
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Dry eye disease (DED) impacts countless individuals, and while therapies like Xiidra® (lifitegrast ophthalmic solution) 5% have proven effective,1 ensuring consistent patient compliance remains a challenge for eye care professionals. Xiidra, which can improve signs and symptoms as early as two weeks,1* is most effective when used consistently. Based on insights shared in the Defocus Media podcast, this article explores practical approaches to improving patient compliance through clear communication, setting expectations, and proactive patient engagement. *Xiidra significantly reduced symptoms of eye dryness at 2 weeks (based on Eye Dryness Score compared to vehicle) in 2 of 4 studies, with improvements observed at 6 and 12 weeks in all 4 studies. Understanding Compliance in Dry Eye Treatment DED is often a chronic, life-impacting condition requiring ongoing management. Patients may not immediately see the value in treating DED, and misunderstandings can cause non-compliance. Xiidra® (lifitegrast ophthalmic solution) 5% can reduce symptoms like dryness and irritation within weeks,1* but adherence is critical to achieving these benefits. As Dr. Jennifer Lyerly noted, explaining the purpose and potential impact of Xiidra is essential to helping patients appreciate its role in long-term ocular health. By emphasizing that regular use can yield noticeable improvements, providers can help patients see the value in their commitment to treatment. *Xiidra significantly reduced symptoms of eye dryness at 2 weeks (based on Eye Dryness Score compared to vehicle) in 2 of 4 studies, with improvements observed at 6 and 12 weeks in all 4 studies. Effective Communication in the Exam Lane Communication is foundational to compliance. Patients need to understand not only their diagnosis but also how Xiidra fits into their overall treatment plan. As Dr. Darryl Glover shared, a well-communicated plan includes a positive, reassuring approach: “I got your back; no worries, we’re in this together.” Language like this reassures patients that their provider is invested in their success and encourages them to stick with the treatment. Tips for Effective Communication: * Use Relatable Terms: Start with familiar language, such as “Your eyes aren’t working as they should,” to ensure patients understand their condition clearly. * Set Clear Expectations: Discuss potential side effects like temporary burning or an altered taste1 so patients know what to expect and aren’t surprised. * Draw Comparisons to Everyday Medications: Dr. Lyerly noted that a simple analogy like comparing Xiidra to blood pressure medication helps patients understand that it only works with consistent use. Building Compliance with Follow-Up Visits Follow-up visits are a powerful tool for reinforcing compliance. Dr. Glover explained that scheduling a follow-up visit provides a critical opportunity to assess patient progress, troubleshoot any issues, and encourage long-term adherence. He also shared that adding a touch of humor or personalization can make follow-up instructions feel less prescriptive and more collaborative, helping patients feel at ease and engaged with their treatment. Dr. Mark Schaefer emphasized that these visits allow both patient and provider to witness the benefits of Xiidra. Dr. Schaefer noted, “Seeing the medication work builds confidence for both the patient and my staff.” The positive reinforcement patients receive during follow-ups can significantly boost compliance rates.
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Ensuring Success: Managing Expectations and Treatment Adherence
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