Ep. 205: Neurofilaments as Biomarkers in ALS and frontotemporal dementia: From Bench to Bedside

Moderator: Raffaele Dubbioso (Naples, Italy) Guest: Andrea Malaspina (London, UK) and Francesco Di Lorenzo (Rome, Italy) In this episode, Raffaele Dubbioso speaks with Andrea Malaspina and Francesco Di Lorenzo about the growing role of neurofilaments as biomarkers in amyotrophic lateral sclerosis and frontotemporal dementia. They discuss the biological basis and clinical interpretation of neurofilament measurements, their diagnostic and prognostic value, and their emerging role in identifying pre-symptomatic disease, monitoring progression, and supporting clinical trials in neurological practice.