Ep. 21 Current HFpEF Treatments: Clinical Pearls & Progress with Dr. Jessica Huston

If your New Year’s resolution involves learning more about current practice guidelines and emerging research on Heart Failure with Preserved Ejection Fraction (HFpEF), you’re in the right place! In this episode of the BackTable Cardiology Podcast, host Dr. Hady Lichaa welcomes heart failure specialist Dr. Jessica Huston to provide a practical update on managing heart failure with preserved ejection fraction (HFpEF). --- SYNPOSIS Dr. Huston and Dr. Lichaa discuss the complexity of diagnosing HFpEF, differences between HFpEF and diastolic heart failure, phenotypes within HFpEF, and treatment strategies, including the use of aldosterone blockers, SGLT-2 inhibitors, and GLP-1 agonists. Dr. Huston emphasizes the importance of phenotyping patients for accurate diagnosis and treatment, and discusses the potential of future therapies and devices. Their conversation also covers the role of inflammation, metabolic syndrome, and the challenges faced in managing fluid balance and hypertension in HFpEF patients. --- TIMESTAMPS 00:00 - Introduction02:20 - Understanding HFpEF05:23 - Phenotypes and Treatment Approaches06:29 - Metabolic Syndrome and HFpEF09:17 - Emerging Treatments and Clinical Trials11:36 - Medication Strategies and Challenges24:51 - Diuretics and Their Limitations31:35 - Advanced Diuretic Strategies35:37 - Hemodynamic Measurements and Their Implications40:02 - Coronary Disease and HFpEF42:52 - Future Directions in Heart Failure Treatment45:45 - Device Therapies and Patient Management49:39 - Concluding Thoughts and Future Prospects --- RESOURCES Dr. Jessica Huston Provider Profilehttps://healthcare.ascension.org/find-care/provider/1073874616/jessica-huston Dr. Hady Lichaa Provider Profilehttps://healthcare.ascension.org/find-care/provider/1336267533/hady-lichaa The SUMMIT Trialhttps://pubmed.ncbi.nlm.nih.gov/39555826/ The TOPCAT Trialhttps://pubmed.ncbi.nlm.nih.gov/24716680/ The FINEARTS Trialhttps://pubmed.ncbi.nlm.nih.gov/39225278/ The CADENCE Trialhttps://www.clinicaltrials.gov/study/NCT04945460