Ep. 219 New Frontiers in Pediatric Hearing Loss: Implants, Gene Therapy, and CMV with Dr. Daniela Carvalho

Are new solutions for pediatric hearing loss finally within earshot? In this episode of the Back Table ENT Podcast, we talk with Dr. Daniela Carvalho, pediatric otolaryngologist and director of the Cochlear Implant Program at Rady Children's Hospital in San Diego. --- SYNPOSIS Dr. Carvalho discusses the latest advancements and practices in the field of pediatric hearing loss, including newer indications for cochlear implants and innovative gene therapies. They delve into the genetic causes of congenital hearing loss, current screening practices, and various gene therapies being tested for hearing deficiencies, such as those involving the OTOF gene and its application through viral vectors. The conversation also touches on the potential for future treatments, including completely implantable cochlear devices and the role of vaccines in preventing CMV-related hearing loss. --- TIMESTAMPS 00:00 - Introduction 01:54 - Understanding Congenital Hearing Loss and Screening 05:41 - Challenges with Older Children and Hearing Loss 08:48 - Cochlear Implants: Indications and Advances 15:59 - Exploring Gene Therapy for Hearing Loss 23:54 - Challenges and Considerations in Gene Therapy 25:23 - Counseling Families on Hearing Loss 27:04 - Future of Genetic Therapy and Cochlear Implants 32:46 - Addressing Congenital CMV 40:59 - Final Thoughts and Future Research --- RESOURCES Dr. Daniela Carvalho https://www.rchsd.org/doctors/daniela-carvalho-md-mmm/