Ep. 24: Does Deuterium Cause Chronic Disease? With Prof. John Speakman

Introduction I am honored to be joined by John Speakman, a leading authority on energy balance in animals, and in the use of the doubly-labeled water method of determining energy balance. This has led him into the study of obesity, among other topics, where he has become a recognized expert. Our discussion was prompted by his recent paper, "Total Daily Energy Expenditure Has Declined Over the Past Three Decades Due to Declining Basal Expenditure, Not Reduced Activity Expenditure", which casts a new light onto the world pandemic of obesity. In addition to discussing a few of the papers that give some background to that one, and his future research plans in light of that paper, we have an enlightening discussion on the potential role of deuterium in obesity and chronic disease. Biography: "John Roger Speakman (born 1958) FRS FRSE FRSB FRSA FMedSci FRSS is a British biologist working at the University of Aberdeen, Institute of Biological and Environmental Sciences, for which he was Director from 2007 to 2011. He leads the University's Energetics Research Group, which is one of the world's leading groups using doubly labeled water (DLW) to investigate energy expenditure and balance in animals. Between 2011-2020, he was  a '1000 talents' Professor at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, in Beijing, China, where he ran the molecular energetics group. In 2020 he moved to the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences in Shenzhen, China where he works at the Center for Energy Metabolism and Reproduction and Head of the Shenzhen Key laboratory of Metabolic Health." https://en.wikipedia.org/wiki/John_Speakman _______________________________________   Tucker Goodrich Substack: https://tuckergoodrich.substack.com/ Twitter: https://twitter.com/TuckerGoodrich Youtube: https://www.youtube.com/tuckergoodrich0 Apple podcast: https://podcasts.apple.com/us/podcast/tucker-goodrich-podcast/id1617481825 Spotify podcast: https://open.spotify.com/show/7wVZ3TnRjGsa1cP2gzWY0y Podcast: https://sites.libsyn.com/408758 Blog (deprecated, but still a lot there!): http://yelling-stop.blogspot.com/ _______________________________________ Show Notes   Boros, Laszlo, Que Collins, and Gábor Somlyai. 2018. "Deuterium and Metabolic Water Matter – What This Means Biochemically and Clinically." September 24. https://www.science.org/doi/10.1126/sciadv.aat7314#elettersSection.     If you have any questions about sources for things discussed please ask in the comments.