Ep. 254 - Takeaways from Grand Rounds 2024

On a special edition of the BioCentury This Week podcast, BioCentury’s editors deliver their takeaways from the debut Grand Rounds conference, which focused on whether biotech can write a more successful playbook for translating from target to product. Weaving together takeaways from the panels, fireside chat and keynote at the conference, the editors assess the tensions between generalizability and fit-for-purpose models, between having control and capturing complexity, and, in human data, between scale and robustness/reliability, particularly for longitudinal readouts. The editors also discuss BioCentury's Q&A with USC Keck School’s Patrick Lyden, who explained how high-quality, reproducible preclinical science can be feasible.View full story: https://www.biocentury.com/article/65363100:00 - Introduction02:56 - Generalizability vs. Fit for Purpose10:03 - Control vs. Complexity17:57 - Scale vs. Robustness in Human Data26:25 - Hypothesis-Driven vs. Unbiased Research28:50 - Grand Rounds 2025To submit a question to BioCentury’s editors, email the BioCentury This Week team at [email protected] us by sending a text