Ep 31. Autonomous Marketing Is Coming — But Brand Still Wins, with Jamie Domenici, Klaviyo episode artwork

EPISODE · Jul 27, 2026 · 44 MIN

Ep 31. Autonomous Marketing Is Coming — But Brand Still Wins, with Jamie Domenici, Klaviyo

from The AI Edge Podcast · host U of Digital

A new Chinese AI model called Kimi K3 just matched frontier model performance at half the cost — and nobody saw it coming. Again. Google launched three new Gemini models in one week, each optimized for different tasks. OpenAI is reportedly building a screenless device with sensors, a camera, and a microphone. And Meta's AI creative tools are generating bikes with two sets of handlebars and telling advertisers it's their problem. This week, Shiv and Myles sit down with Jamie Domenici, CMO of Klaviyo — the B2C CRM powering over 200,000 brands and eight billion messages a day. Jamie brings a rare perspective to the show: she's a marketer leading marketing for a marketing platform, which means she's living the AI transformation from both sides of the table simultaneously. Jamie breaks down why the autonomous marketing future is closer than most people think — and why human judgment is still the thing that separates the brands that win from the ones that just move fast. She explains why you can't just turn on an agent and let it rip, why brand guidelines need to be trained into your AI from day one, and why the companies embracing AI right now are already building more, personalizing better, and outrunning the competition. She also shares how Klaviyo used AI to automate their entire product release workflow — from engineering ship to blog post — because the pace of AI-driven releases made the old way completely unsustainable. They also get into why ChatGPT's contextual targeting is fundamentally different from Meta's blunt retargeting, why voice AI hasn't disrupted marketing yet but is about to, and why every marketer needs to start thinking about how their brand shows up in places they've never had to optimize for before — including image search, LLMs, and whatever screenless device OpenAI ships next. Ready to level up your AI skills? Join the U of Digital AI Accelerator. Enrollment now open for September | Sponsored by Blis, part of T-Mobile Advertising Solutions https://uof.digital/ai/accelerator/ New episodes every two weeks. Get your AI Edge here.

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Ep 31. Autonomous Marketing Is Coming — But Brand Still Wins, with Jamie Domenici, Klaviyo

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