Ep. 310: “Epithelial Organoids” Featuring Dr. Hans Clevers

Guest: Dr. Hans Clevers is a Professor of Molecular Genetics and Distinguished Group Leader at the University of Utrecht. In this episode, he discusses snake gut and lung organoids, transitioning from academia to industry, and the challenges and complexities of creating a cell therapy. (44:26) Featured Products and Resources: Registration and abstracts are open for the ISSCR 2026 annual meeting. Receive an offer to try IntestiCult in your lab. The Stem Cell Science Round Up Computers Made From Human Brain Cells – Researchers have shown that structured neuronal firing sequences appear in spontaneous activity of human and murine brain organoids. (2:37) Organoids Replicate Vascular Pathology – Scientists have developed a blood vessel organoid model from Hutchinson-Gilford progeria syndrome-mutant hESCs. (12:01) Effects of Spaceflight on Stem Cells – Analyses of nine astronauts before, during, and after three short-duration International Space Station missions shows space-associated stem cell hallmarks of aging and resilience. (21:14) The Role of Lysosomes in HSC Aging – Reversing lysosomal dysfunction restores youthful state in aged hematopoietic stem cells. (33:25) Photo Reference: Courtesy of Hans Clevers <div id="footable_parent_5807" class=" footable_parent ninja_table_wrapper loading_ninja_table wp_table_data_press_parent semantic_ui "> <table data-ninja_table_instance="ninja_table_instance_26" data-footable_id="5807" data-filter-delay="1000" aria-label="Global Sidebar Ad One" id="footable_5807" data-unique_identifier="ninja_table_unique_id_3026692176_5807" class=" foo-table ninja_footable foo_table_5807 ninja_table_unique_id_3026692176_5807 ui table nt_type_ajax_table selectable striped vertical_centered footable-paging-right"> <div id="footable_parent_5808" class=" footable_parent ninja_table_wrapper loading_ninja_table wp_table_data_press_parent semantic_ui "> <table data-ninja_table_instance="ninja_table_instance_27" data-footable_id="5808" data-filter-delay="1000" aria-label="Global Sidebar Ad Two" id="footable_5808" data-unique_identifier="ninja_table_unique_id_3819333052_5808" class=" foo-table ninja_footable foo_table_5808 ninja_table_unique_id_3819333052_5808 ui table nt_type_ajax_table selectable striped vertical_centered footable-paging-right"> Subscribe to our newsletter! Never miss updates about new episodes. Subscribe