EPISODE · Jul 22, 2026 · 1H 5M
Ep 383 - Q&A: Imbalances, Fatigue, & REDs
from Iron Culture presented by MASS · host MASS Research Review
In today's Q&A episode, the Erics work through a few listener questions. First they tackle upper/lower body imbalance — why lagging body parts usually call for improving training quality before adding volume, and why standout muscle groups can be maintained on surprisingly little work. Next is a long discussion on managing fatigue and exercise sequencing in high-frequency, non-traditional splits, including why the "48 hours between muscle groups" rule is more dogma than requirement and how to think about fatigue as continuous rather than categorical. The episode closes with a multifaceted question on REDs (relative energy deficiency in sport) — what it is, its warning signs, and the limits of what bloodwork can actually tell you. Iron Culture is proudly presented by the MASS Research Review. Mostly because Helms and Trex are co-owners.massresearchreview.comIf you're in the market for some new (ultra-high-quality) gym gear or apparel, be sure to use code "MRR10" for a 10% discount over at elitefts.comIf you'd like to submit a question for a future episode, head over to:massresearchreview.com/ironcultureChapters0:00 Intro4:25 Fixing upper/lower body imbalance6:39 Quality before quantity9:03 Why standout muscles hold with less work12:25 Fatigue & sequencing high-frequency training17:58 How to actually sequence back-to-back days23:56 Lifting "rules" set in concrete26:09 Are lifters too worried about fatigue?39:34 REDs (relative energy deficiency in sport)40:51 Liver enzymes, creatinine & training stress46:07 Cholesterol/LDL & other markers1:00:21 Wrap-up
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Ep 383 - Q&A: Imbalances, Fatigue, & REDs
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