EP 42: Perimenopause series: The Estrogen Drama episode artwork

EPISODE · Jan 4, 2026 · 1H 5M

EP 42: Perimenopause series: The Estrogen Drama

from Hump Day Hormones

Ever feel like your hormones are on a rollercoaster with no seatbelt? Welcome to perimenopause – or as some have called it, “puberty in reverse.” In honor of Perimenopause Awareness Month, we’re back with part two of our special series, and this week it’s all about estrogen: the multitasking, drama-filled hormone that keeps your brain, bones, heart, and skin in balance... until it doesn’t. Last week, Jackie Piasta helped us unpack why perimenopause is finally getting the attention it deserves as millennials begin “hitting the pause.” Today, we dive into why estrogen is so unpredictable during this transition and why progesterone seems to skip the invite altogether. From heavy periods one month to hot flashes and night sweats the next, estrogen’s highs and lows can leave women feeling like they’re living in hormonal whiplash. We’ll break down the stages of perimenopause, talk through what estrogen dominance really means (and why mainstream medicine side-eyes the term), and explore the real-life symptoms women face daily—brain fog, anxiety, sleep struggles, mood swings, libido changes, and more. Think of it as decoding the chaos so you can finally understand what’s happening inside your body. This episode is fun, raw, and empowering, with practical takeaways that will leave you feeling less alone and more equipped to handle this transition. Because perimenopause isn’t just about periods—it’s a full-body journey. And understanding estrogen’s drama is the first step in taking back control.

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EP 42: Perimenopause series: The Estrogen Drama

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