Ep. 43 - Hormone Replacement Therapy: Past to Present (Part 1) - with Marie Hoag & Anthony Llabres

This is the first of three episodes diving into Bioidentical Hormone Replacement Therapy (or BHRT). I’ll be joined by two guests, Marie Hoäg and Anthony Llabres, to cover what BHRT is and everything you might want to know about it.   If you have any questions you’d like answered along the way, please reach out to me by email: thomunderwood.net/contact.   Marie is an independent clinical hormone medicine consultant for patients and healthcare practitioners. She has an extensive professional hormone coaching background, working for over 15 years in a specialty hormone medicine clinic with thousands of male and female, cisgender and transgender patients. She has experience with all forms of hormone therapy, both as a clinician coach and through personal experience as a hormone patient utilizing virtually every method and kind of hormone therapy available.   Marie is also the founder and CEO of Panacea Sciences, a research and educational health sciences company that offers advanced education and clinical application training for physicians and physician extenders who want to learn how to intelligently administer advanced bioidentical hormone therapy to get women’s hormones to their “Hormone Sweet Spot”™.   Anthony Llabres is a Certified Functional Diagnostic Nutrition Practitioner (FDN-P). He has also been certified through the world-renowned Kalish Institute/Kalish Practitioner. As a Certified Practitioner, he is able to work with clients around the world in advancing their health and wellness goals. With the Functional Approach, he can work on underlying body systems such as the hormone, immune, digestive, detoxification, and brain systems.   Hormone Replacement Therapy Then & Now - for Women   Many women and doctors think there's only one way to "balance" hormones and only one kind of Hormone Replacement Therapy – but the truth is, there are four generations of hormone replacement therapy, and each generation has different clinical outcomes.   Below is a breakdown of each generation, offered by Marie:   1st Generation - Oral pills, synthetic, lowest dose possible for the shortest amount of time, static dosing, no real education/training, and stops working in weeks.   2nd Generation - Compounded, bioidentical (this is the biggest difference between generation one and two), lowest dose possible for the shortest amount of time, static doses, some education (but not a lot), no clinical application training, designed to treat symptoms of hormone deficiencies (but not fix them), and stops working in months.   3rd Generation - Compounded, bioidentical, derived from a plant but still synthesized, medium dose, rhythmically administered (mimicking the natural physiology of each hormone), minimal theory education, no clinical application training. It’s better than 1st and 2nd generation in terms of clinical outcomes, but still only about 20% effective.   4th Generation - Compounded, bioidentical, physiological dosing (doses mimic a woman’s hormones in her reproductive prime), clinically effective dosing schedule, rhythmically administered, clinical algorithm, standardized customizable system, eliminates hormone deficiencies (not just the symptoms), 80-90% clinically effective, and sustainable “Hormone Sweet Spot”™.   A big part of the 4th generation’s success is because the size and schedule of the doses more closely mimic natural hormone cycles. You can see in Moxie’s chart that