Ep 46-Don't Die: Bryan Johnson and Longevity Science

Send us Fan MailA cookie-fueled cold open gives way to one of the thorniest questions in modern medicine: are we getting healthier, or just better at making numbers look good? Using Brian Johnson’s “Blueprint” as a case study, we unpack the science behind epigenetic clocks, the appeal of tight control, and the lesson medicine keeps relearning—lowering a risky marker isn’t the same as improving a life. We trace hard-won examples from ICU glucose control to HRT and anti-arrhythmics, then map that history onto today’s longevity culture, where proxies move fast and outcomes arrive slow.Enjoy the ride, laugh at the holiday detours, and leave with a pragmatic checklist: sleep on purpose, move daily, eat simply, and be skeptical when a perfect metric is sold as a cure. If this resonated, follow the show, share it with a friend, and leave a quick review—your support helps us keep the conversation honest and useful.Resources: Steve Horvath’s original epigenetic clock (2013, Genome Biology)National Law Review+1BryanJohnson.comGrimAge and PhenoAge models (Aging, Nature Communications)DunedinPACE (eLife, 2022)Home | CALERIEAmerican Federation for Aging Research+1The Documentary “Don’t Die: The Man Who Wants to Live Forever” on Netflix Support the showDon't miss a (heart) beat! Check out our Instagram @doctoringthetruthpodcast and email us your Medical Mishaps at [email protected]. Join us on Facebook at Doctoring the Truth, and TikTok @doctoring the truth. Don't forget to download, rate, and review so we can keep bringing you more exciting content each week!Stay safe, and stay suspicious...trust, after all, is a delicate thing!Don't forget to check out these fantastic discounts using promo code STAYSUSPICIOUS from our sponsors at:*thecuminclub.com for 30% off*https://strongcoffeecompany.com/discount/STAYSUSPICIOUS for 20% off*www.handful.com for 30% off *www.standshoes.com for 15% off*www.oldglory.com for 15% off*www.getcheeky.com for 30% off*https://mollybz.com for 10% off *www.RSRVCollective.com for 30% off *klearprotein.com for 20% off*www.torrain.org for 15% off*www.cozyearth.com for 21% off* www.yarokhair.com for 15% off  *www.loveindus.com for 21% off ...