Ep. 56 Breast Cancer Precision Medicine: Biomarkers & Treatments with Dr. Jessica Treviño Jones

Here’s a practical guide on how biomarkers can guide treatment and cut costs for your breast cancer patients. In this episode of the BackTable Tumor Board Podcast, Dr. Lindsay Peterson and Dr. Jessica Trevino Jones review the role of precision medicine and biomarkers in early-stage and metastatic disease, specifically in breast cancer. --- Get the BackTable apphttps://www.backtable.com/app --- Timestamps 00:00 - Introduction05:30 - Genomic Testing in the Metastatic Setting11:47 - Liquid vs Tissue Biopsy17:51 - Testing and Treatment for Triple Negative Metastatic Breast Cancer21:20 - Precision Medicine and Patient Education27:01 - Path CR and Residual Disease: Clinical Trials37:01 - Neratinib in Triple Positive Breast Cancer and Brain Metastasis39:55 - Genomic Tests: Oncotype and MammaPrint43:45 - Importance of Clinical Trials and Wellness Support --- More about this episode Dr. Peterson and Dr. Trevino Jones discuss the optimal timing for tumor genomic testing in ER-positive/HER2-negative and triple-negative metastatic breast cancer, and examine the decision-making process between liquid biopsy and tissue biopsy for biomarker analysis. The conversation also highlights how these technological advances can expand treatment options and help reduce financial toxicity for patients. Additionally, the doctors emphasize the importance of patient education about clinical trials, address common misconceptions, and discuss the integration of prevention, nutrition, exercise, and wellness support into comprehensive cancer care. --- Resources OFSET Clinical Trialhttps://clinicaltrials.gov/study/NCT05879926 SWOG 2206 Clinical Trialhttps://www.swog.org/clinical-trials/s2206 Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Path CRhttps://clinicaltrials.gov/study/NCT05812807 KETNOTE-522 Clinical Trialhttps://clinicaltrials.gov/study/NCT03036488https://www.nejm.org/doi/full/10.1056/NEJMoa1910549 --- BackTable Tumor Board is the go-to multidisciplinary podcast for medical oncologists, surgical oncologists, and other healthcare professionals that play an active role in cancer care. Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty. ► https://www.backtable.com/app