EP 79: The Essential Fatty Acid You’ve Never Heard Of: Danielle Cole on the Power of C15 episode artwork

EPISODE · Sep 11, 2025 · 32 MIN

EP 79: The Essential Fatty Acid You’ve Never Heard Of: Danielle Cole on the Power of C15

from Longevity Unlocked · host Dr. K and Coach Kyle

Episode Summary In this episode of the Peak Performance Podcast, Coach Kyle sits down with Danielle Cole, Head of Sales at Fatty15, to uncover the fascinating science behind C15 (pentadecanoic acid) — a newly recognized essential fatty acid. Danielle shares how her background in biochemistry and years in integrative medicine led her to join Fatty15, a company rooted in breakthrough research that began with the U.S. Navy’s dolphin program. The conversation dives into how C15 improves mitochondrial function, cellular signaling, and overall metabolic health, while also addressing its role in pregnancy, cardiovascular health, and even potential cancer research. Kyle and Danielle discuss dosing strategies, comparisons with omega-3s, and what makes C15 unique as a saturated fat that resists oxidative stress. Kyle also shares personal stories about using Fatty15 himself, his wife’s remarkable pregnancy experience while supplementing with it, and how biohackers might experiment with higher doses for performance and longevity. Whether you’re curious about cellular optimization, pregnancy health, fatty acid science, or practical biohacking strategies — this episode is packed with cutting-edge insights and real-world stories. Key Takeaways What C15 (pentadecanoic acid) is and why it was only recently classified as an essential fatty acid The surprising discovery of C15’s importance through U.S. Navy dolphin research How C15 supplementation can improve mitochondrial function by up to 45% and enhance ATP production The role of C15 in pregnancy outcomes, labor efficiency, and child development Why most people are deficient in C15 due to modern diets, and the best dietary sources The difference between C15 and omega-3 fatty acids, and why omega-3 supplements may not always be necessary Clinical findings on C15’s effect on cholesterol, triglycerides, insulin response, and cellular aging Anecdotal and early evidence of anti-cancer activity and implications for long-term health How biohackers are experimenting with higher dosing strategies for optimization   Chapters 00:00 Introduction & Danielle’s Background in Nutrition & Biochemistry 02:30 What Is Fatty15? The Discovery of C15 as an Essential Fatty Acid 04:15 The U.S. Navy Dolphin Research That Started It All 06:00 Kyle’s Personal Experience with Fatty15 & His Wife’s Pregnancy Journey 08:30 Pregnancy Outcomes, Mitochondrial Function, and ATP Production 12:00 C15 in Baby Formula and Childhood Development Research 15:00 Dosage Strategies: From Deficiency to Optimization 18:00 Comparing C15 and Omega-3s: Do You Still Need Fish Oil? 20:30 Longevity, Performance, and the mTOR/AMPK Pathways 24:50 C15’s Effect on Cholesterol, Triglycerides & Cardiovascular Health 26:40 High-Dose Biohacking, Lipid Optimization, and Cancer Research 30:15 Future of Fatty15: Higher-Dose Formulas and Accessibility 32:45 Final Thoughts: Diet, Lifestyle, and Essential Nutrients Sponsors This episode is sponsored by The Longevity Center FL Your one-stop natural medicine shop. The LCFL is the perfect blend of Integrative, Osteopathic, and Regenerative Health Care in West Palm Beach, FL. Location: 580 Village Blvd #210, West Palm Beach, FL 33409 Website: https://www.thelcfl.com/ Instagram: https://www.instagram.com/thelcfl.com   Credits Produced by: Clearview Studio Filmed by: Jackson Young with @clearviewstudios   People & Social Links Podcast Website: https://peakperformancepodcast.online/ Instagram: @thepeakperformancepod X (Twitter): @PeakPerformPod Dr. K on Instagram: @theosteodoc   Guest Danielle Cole Vice President of Sales of Fatty15 Website: https://www.discoverc15.com/#                https://fatty15.com

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