Ep339: What’s Really Driving Your Weight Loss Resistance After 40? with Curtis Gillespie Sayers episode artwork

EPISODE · May 26, 2026 · 1H 3M

Ep339: What’s Really Driving Your Weight Loss Resistance After 40? with Curtis Gillespie Sayers

from Fit + Fueled Life Podcast

In this episode, Tina sits down with Curtis to dig into what’s really behind weight loss resistance after 40. Because for a lot of women, it’s not just about calories, macros, or workouts. It’s everything happening underneath: chronic stress, inflammation, under-eating, nervous system overload, and a body that’s quietly shifting into protection mode in midlife. They also talk about why fat loss can suddenly stall, what most people miss when they try to “push harder,” and how things like detox pathways, recovery, and unresolved stress load all show up in body composition. If you’ve been doing more and getting less back, this conversation helps connect a lot of those dots. Here’s what you’ll learn: - The real reason you can't lose weight has nothing to do with your macros or your workouts - Why your body is literally designed to hold onto fat and what has to happen before it will let go - The connection between unresolved trauma and weight loss resistance that Curtis sees in almost every woman who has tried everything - Detox is fat loss: what this actually means and why your ability to detoxify determines whether your body will release fat - Why under-eating is making fat loss harder and the slow strategic way to fix it - What food noise is actually telling you and why a GLP-1 not quieting it down is a very specific clue - The training style most women swear by that Curtis says is creating more inflammation than results - Why your body will never prioritize building muscle when you are under-eating and inflamed - The mitochondrial peptides everyone is using for fat loss that Curtis thinks are being used completely backwards - Why MOTS-c works great for some women and causes serious reactions in others - Two books that have changed more of his clients' biology than any peptide or supplement - Why Curtis uses SLU-PP-332 for the exact opposite reason most people think Subscribe: https://carrotsncake.substack.com Join Fit + Fueled: https://carrots-n-cake.mykajabi.com/fit+fueled Why GLPs Fail Recording: https://carrotsncake.kit.com/fpm Connect with Tina Haupert: https://carrotsncake.com/ Facebook: Carrots 'N' Cake https://www.facebook.com/carrotsncake Instagram: @carrotsncake https://www.instagram.com/carrotsncake YouTube: Tina Haupert https://www.youtube.com/user/carrotsncake About Tina Haupert: Tina Haupert is the owner of Carrots ‘N’ Cake as well as a Certified Nutrition Coach and Functional Diagnostic Nutrition Practitioner (FDN-P). Tina and her team use functional testing, peptides, and a personalized approach to nutrition to help women find balance within their diets while achieving their body composition goals. Connect with Curtis Gillespie Sayers: https://lifestylempowerment.ca/ Facebook: https://www.facebook.com/1lifeestyleempowerment/ Youtube: https://www.youtube.com/@curtisfunctionalhealthcoach Instagram: https://instagram.com/that.coach.curtis About Curtis Gillespie Sayers: From a young age I was in and out of the hospital suffering from health complications for as long as I can remember, breathing difficulties being the most apparent but as I grew older more serious issues began to come to light. I was diagnosed with an extremely severe case of sleep apnea, high blood pressure, high cholesterol, and a pre-diabetic status. At this time, I was also struggling with substance abuse, which would obviously contribute to my health complications, but most were from birth. After receiving the news from running tests, the doctors had informed me that I was lucky to be alive. My psychological health was greatly impacted by my physiological health, evoking feelings of anger, and negativity which caused me to constantly argue with people around me. This affected several of my relationships and was creating a miserable life.

In this episode, Tina sits down with Curtis to dig into what’s really behind weight loss resistance after 40. Because for a lot of women, it’s not just about calories, macros, or workouts. It’s everything happening underneath: chronic stress, inflammation, under-eating, nervous system overload, and a body that’s quietly shifting into protection mode in midlife. They also talk about why fat loss can suddenly stall, what most people miss when they try to “push harder,” and how things like detox pathways, recovery, and unresolved stress load all show up in body composition. If you’ve been doing more and getting less back, this conversation helps connect a lot of those dots. Here’s what you’ll learn: - The real reason you can't lose weight has nothing to do with your macros or your workouts - Why your body is literally designed to hold onto fat and what has to happen before it will let go - The connection between unresolved trauma and weight loss resistance that Curtis sees in almost every woman who has tried everything - Detox is fat loss: what this actually means and why your ability to detoxify determines whether your body will release fat - Why under-eating is making fat loss harder and the slow strategic way to fix it - What food noise is actually telling you and why a GLP-1 not quieting it down is a very specific clue - The training style most women swear by that Curtis says is creating more inflammation than results - Why your body will never prioritize building muscle when you are under-eating and inflamed - The mitochondrial peptides everyone is using for fat loss that Curtis thinks are being used completely backwards - Why MOTS-c works great for some women and causes serious reactions in others - Two books that have changed more of his clients' biology than any peptide or supplement - Why Curtis uses SLU-PP-332 for the exact opposite reason most people think Subscribe: https://carrotsncake.substack.com Join Fit + Fueled: https://carrots-n-cake.mykajabi.com/fit+fueled Why GLPs Fail Recording: https://carrotsncake.kit.com/fpm Connect with Tina Haupert: https://carrotsncake.com/ Facebook: Carrots 'N' Cake https://www.facebook.com/carrotsncake Instagram: @carrotsncake https://www.instagram.com/carrotsncake YouTube: Tina Haupert https://www.youtube.com/user/carrotsncake About Tina Haupert: Tina Haupert is the owner of Carrots ‘N’ Cake as well as a Certified Nutrition Coach and Functional Diagnostic Nutrition Practitioner (FDN-P). Tina and her team use functional testing, peptides, and a personalized approach to nutrition to help women find balance within their diets while achieving their body composition goals. Connect with Curtis Gillespie Sayers: https://lifestylempowerment.ca/ Facebook: https://www.facebook.com/1lifeestyleempowerment/ Youtube: https://www.youtube.com/@curtisfunctionalhealthcoach Instagram: https://instagram.com/that.coach.curtis About Curtis Gillespie Sayers: From a young age I was in and out of the hospital suffering from health complications for as long as I can remember, breathing difficulties being the most apparent but as I grew older more serious issues began to come to light. I was diagnosed with an extremely severe case of sleep apnea, high blood pressure, high cholesterol, and a pre-diabetic status. At this time, I was also struggling with substance abuse, which would obviously contribute to my health complications, but most were from birth. After receiving the news from running tests, the doctors had informed me that I was lucky to be alive. My psychological health was greatly impacted by my physiological health, evoking feelings of anger, and negativity which caused me to constantly argue with people around me. This affected several of my relationships and was creating a miserable life.

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Ep339: What’s Really Driving Your Weight Loss Resistance After 40? with Curtis Gillespie Sayers

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This episode is 1 hour and 3 minutes long.

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This episode was published on May 26, 2026.

What is this episode about?

In this episode, Tina sits down with Curtis to dig into what’s really behind weight loss resistance after 40. Because for a lot of women, it’s not just about calories, macros, or workouts. It’s everything happening underneath: chronic stress,...

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