EPISODE · Dec 15, 2025 · 16 MIN
EP36:減重神藥(Tirzepatide)停用後?心臟代謝指標逆轉的真相
from Med x Decode (中文) · host MedxDecode.com
很多人問:成功減重後,可以停用Tirzepatide(替爾泊肽,一種GIP/GLP-1受體促效劑)嗎?SURMOUNT-4的最新分析揭示了一個關鍵事實:停藥後體重回升是常態,且回升幅度越大,先前改善的心臟代謝健康指標(例如腰圍、血壓、血糖)惡化得越快。這項研究強調了肥胖治療是一場必須持續下去的「長期作戰」。 資料引用 (References):Horn DB, Linetzky B, Davies MJ, et al. Cardiometabolic Parameter Change by Weight Regain on Tirzepatide Withdrawal in Adults With Obesity A Post Hoc Analysis of the SURMOUNT-4 Trial. JAMA Intern Med. doi:10.1001/jamainternmed.2025.6112 (Published online November 24, 2025).Oczypok E, Anderson TS. Lessons Learned From Antiobesity Medication Withdrawal Trials. JAMA Intern Med. doi:10.1001/jamainternmed.2025.6058 (Published online November 24, 2025). 加入會員,支持節目: https://medxdecode.firstory.io/join 留言告訴我你對這一集的想法: https://open.firstory.me/user/cmf1wvrez00n601tzbbmackvx/comments Powered by Firstory Hosting
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EP36:減重神藥(Tirzepatide)停用後?心臟代謝指標逆轉的真相
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