Episode 1: Introduction/MDMA Therapy for PTSD

Introducing the Neural Pharm Podcast, featuring your hosts Colby Burns, PharmD, and Christopher Toney, PharmD. Episode 1 establishes the mission of the podcast, and covers the groundbreaking MAPP1 and MAPP2 trials that established MDMA as a breakthrough therapy for PTSD. We also cover key safety data including drug interactions, pharmacokinetics (or metabolism), and pharmacogenomics (or gene-drug interactions). Come join us!

***Correction Alert: The Ted talk referenced by Colby in the conclusion of the podcast was given by Dr. Ben Sessa, not Sassa (see the attached video in the reference section)****

References:

* Mitchell J, et al. MDMA Assisted Therapy for Severe PTSD: A randomized, double blind, placebo controlled phase 3 study. Nature. 10 May 2021 <https://www.nature.com/articles/s41591-021-01336-3>

* Mental Health By the Numbers. National Alliance on Mental Illness. 2023.

* Sessa B, et al. A Review of 3,4-methylenedioxymethamphetamine (MDMA) Assisted Psychotherapy. 2019(10).

* Sessa B. Is MDMA psychiatry’s antibiotic? Tedx University of Bristol. 5 July 2016.

See video below.

* Silverstone P. The Promise of Psychedelics: Science Based Hope for Better Mental Health. 2022 Apr 21. Ingenium books. 

Referenced in podcast to be discussed in future episode:

Christie D, Kryskow P. MDMA Assisted Psychotherapy for Fibromyalgia and Other Centralization Syndromes. Psychedelics Today (podcast). 21 Feb 2023