Episode 103 - On The Wards: Breaking Bad . . . Cells | Tumour Lysis Syndrome

from Bloody Minded · host Bloody Minded Crew

Have you been asked to review “TLS” bloods?? Are you concerned the nursing staff are pranking you with haematology bloods that don’t include a FBC or coags? Why could you possibly want to look at something that isn’t a cell count? What crazy person decided after hours bloods needed to be collected on ICE? And WHY ?!?! Join us for an On The Wards approach to dealing with those TDS TLS SOS calls.TIMESTAMPS:0:56 - The team breaking stuff3:40 - Episode overview5:07 - Setting the scene6:33 - The history of TLS7:28 - (nailed it)8:00 - Pathophysiology of TLS10:41 - Mechanisms of renal injury in TLS11:39 - Clinical consequences of TLS12:46 - Diagnostic criteria in TLS15:10 - Clinical TLS vs lab TLS15:35 - Grading TLS16:55 - Other clues of TLS18:09 - Who is at risk of TLS?23:15 - Prevention of TLS24:27 - Allopurinol26:58 - Rasburicase33:03 - Fluids fluids fluids33:44 - Deciding who gets prophylaxis35:50 - What ARE TLS bloods?36:31 - What to do with a TLS on the ward40:05 - Take home messagesSupport the showCheck out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

Episode metadata supplied by the publisher feed · Published Sep 1, 2026

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Episode 103 - On The Wards: Breaking Bad . . . Cells | Tumour Lysis Syndrome

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